A case report of leptospira grippotyphosa in the Azerbaijan buffalo in Iran

Abstract

Leptospirosis is an infectious disease of all species. In cows and buffalos cause abortion and haemolytic anaemia with an interstitial nephritis. On april 2003 a 6 years old female buffalo (azarbijan black buffalo) was observed in large animal clinic of tabriz azad university. In this case the clinical findings were: fever (39.1), depression, anorexia, decrease of milk production, anaemia , jaundice, haemoglobinuria, heart rate 82 per minute and respiratory rate 18 per minute. Kidnay, in rectal examination detected neutrophilia and leukocytosis. Total plasma protein and fibrinogen were 6.8 g/dl and 600 mg/dl respectivly. In urine examination was observed haemoglobinuria and proteinuria with increase of leukocytes. The leptospira was seen in urine by darkfeild microscope and microscopic agglotination test (MAT) detected serovar of leptospira grippotyphosa with titre of 400. Treatment was recommended with 20000 Iu/kg penicillin G procaine , 20 mg/ kg dihydrostreptomycin and vitamin B12 every day and vitamin AD3E ingected single dose. In period of treatment this case monitored every day. The care was taken gradually, so that, haemoglobinuria was eliminated in four days and heamatologic station was returned to normal in eight days. Treatment was continued three days after care. The MAT titre was 100 after five mouths.